5-(O-methoxyphenoxy)-2-pymidin-2-yl)-4,6-(1H,5H)-pymidine dione
5-(2-methoxyphenoxy)-[2,2'-bipyrimidine]-4,6(1h,5h)-dione
CAS: 150728-12-4
Molecular Formula: C15H12N4O4
5-(O-methoxyphenoxy)-2-pymidin-2-yl)-4,6-(1H,5H)-pymidine dione - Names and Identifiers
| Name | 5-(2-methoxyphenoxy)-[2,2'-bipyrimidine]-4,6(1h,5h)-dione |
| Synonyms | Bosentan interMediate 5-(2-Methoxyphenoxy)-[2,2'-BipyriMidine]-4,6(1H,5H)- 5-(2-methoxyphenoxy)-2,2'-bipyrimidine-4,6(1H,5H)dione 5-(2-Methoxyphenxoy)-[2,2'-bipyrimidine]-4,6(1H,5H)-dione 5-(2-methoxyphenoxy)-[2,2'-bipyrimidine]-4,6(1h,5h)-dione 5-(O-methoxyphenoxy)-2-pymidin-2-yl)-4,6-(1H,5H)-pymidine dione 5-(2-methoxyphenoxy)-2-(pyrimidin-2-yl)pyrimidine-4,6(1H,5H)-dione 5-(2-Methoxyphenoxy)-2-(pyriMidin-2-yl)-1,4,5,6-tetrahydropyriMidine-4,6-dione |
| CAS | 150728-12-4 |
| EINECS | 604-748-4 |
| InChI | InChI=1/C15H12N4O4/c1-22-9-5-2-3-6-10(9)23-11-14(20)18-13(19-15(11)21)12-16-7-4-8-17-12/h2-8,11H,1H3,(H,18,19,20,21) |
5-(O-methoxyphenoxy)-2-pymidin-2-yl)-4,6-(1H,5H)-pymidine dione - Physico-chemical Properties
| Molecular Formula | C15H12N4O4 |
| Molar Mass | 312.28 |
| Density | 1.45 |
| Appearance | White powder |
| pKa | 6.23±0.40(Predicted) |
| Storage Condition | 2-8°C |
| Refractive Index | 1.676 |
5-(O-methoxyphenoxy)-2-pymidin-2-yl)-4,6-(1H,5H)-pymidine dione - Introduction
5-(2-methoxyphenoxy)-[2,2 '-bipyrimidine]-4,6(1H, 5h)-dione is a chemical compound also known as FMK(Fluorescein IsoThioMethane Ketone). The following is a description of the properties, uses, preparation and safety information of the compound:
Properties: 5-(2-methoxyphenoxy)-[2,2 '-bipyrimidine]-4,6(1H, 5h)-dione is a blue crystal, it can be dissolved in an organic solvent. Its molecular formula is C15H11N3O3S and its molecular weight is 309.33g/mol. The compound is sensitive to light and emits green fluorescence when exposed to light.
use: 5-(2-methoxyphenoxy)-[2,2 '-bipyrimidine]-4,6(1H, 5h)-dione is commonly used as a fluorescent probe, it is used to detect and study protein activity and structure, especially the activity of cysteine proteases and some other enzymes. It can also be used in the study of apoptosis and cell proliferation.
preparation method: the synthesis method of 5-(2-methoxyphenoxy)-[2,2 '-bipyrimidine]-4,6(1H, 5h)-dione is more complicated, it is generally synthesized by a multi-step reaction. The main method is the condensation of 2-methoxyaniline and dipyrimidine to give 2-(2-methoxyaniline) pyrimidine, and then the target product is produced by oxidation and elimination reactions.
Safety information: About 5-(2-methoxyphenoxy)-[2,2 '-bipyrimidine]-4,6(1H, 5H)-The safety information of dione has not been reported in detail. However, as a chemical, it can pose certain risks to health and the environment. During use, follow proper laboratory safety operations, avoid contact with skin, eyes or inhalation of gas, and operate in a well-ventilated environment. In case of accidental contact or ingestion, seek medical advice immediately and provide detailed information on the chemical.
Properties: 5-(2-methoxyphenoxy)-[2,2 '-bipyrimidine]-4,6(1H, 5h)-dione is a blue crystal, it can be dissolved in an organic solvent. Its molecular formula is C15H11N3O3S and its molecular weight is 309.33g/mol. The compound is sensitive to light and emits green fluorescence when exposed to light.
use: 5-(2-methoxyphenoxy)-[2,2 '-bipyrimidine]-4,6(1H, 5h)-dione is commonly used as a fluorescent probe, it is used to detect and study protein activity and structure, especially the activity of cysteine proteases and some other enzymes. It can also be used in the study of apoptosis and cell proliferation.
preparation method: the synthesis method of 5-(2-methoxyphenoxy)-[2,2 '-bipyrimidine]-4,6(1H, 5h)-dione is more complicated, it is generally synthesized by a multi-step reaction. The main method is the condensation of 2-methoxyaniline and dipyrimidine to give 2-(2-methoxyaniline) pyrimidine, and then the target product is produced by oxidation and elimination reactions.
Safety information: About 5-(2-methoxyphenoxy)-[2,2 '-bipyrimidine]-4,6(1H, 5H)-The safety information of dione has not been reported in detail. However, as a chemical, it can pose certain risks to health and the environment. During use, follow proper laboratory safety operations, avoid contact with skin, eyes or inhalation of gas, and operate in a well-ventilated environment. In case of accidental contact or ingestion, seek medical advice immediately and provide detailed information on the chemical.
Last Update：2024-04-10 22:29:15
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